Select Language


Treating Chronic Lyme Disease with Antabuse (disulfiram)

There is an exciting possibility that Antabuse (disulfiram) can effectively treat, and possibly even cure, chronic Lyme disease. Antabuse has been used for years to discourage alcoholics from consuming alcohol, because consuming even small amounts when taking this drug can cause a terrible hangover. But it turns out that disulfiram also has antibiotic properties. Lab experiments found that disulfiram was significantly more effective at killing Borrelia burgdorferi (the bacteria that causes Lyme disease) than other antibiotics commonly used to treat it, and in some cases, disulfiram completely eradicated this bacteria. The jury is still out about disulfiram’s effectiveness in humans, but initial case reports of Lyme patients who are trying disulfiram are positive. One patient who took disulfiram for four months has remained symptom-free for two years after discontinuing the drug. For more information about treating chronic Lyme disease with Antabuse (disulfiram), see this excellent article by Dan Kinderlehrer, MD, “Disulfiram-breakthrough drug for Lyme and other tick-borne diseases?”